Sunday, 7 September 2014

AstraZeneca boosted by start of new cancer drug trial

Hopes are boosted for colorectal cancer patients with the news that AstraZeneca had moved its immuno-oncology medicine MEDI-4736 into a mid-stage study in colorectal cancer. The drug, which is designed to help the immune system fight tumours, will be tested in 48 patients with advanced disease in the Phase II trial. AstraZeneca is already studying MEDI-4736 in lung cancer and head and neck cancer.
MEDI-4736 is part of a closely-watched class of drugs known as anti-PD-L1 therapies, which block a tumour's ability to evade the immune system's defences. MEDI-4736 is seen as AstraZeneca's most important new drug hope and it was one of several experimental products flagged by the company in May in a bid to convince investors the group has a healthy future as an independent company.
The new open-label Phase II study, which is not yet open for patient recruitment, is being run by the New York-based Memorial Sloan-Kettering Cancer Center in collaboration with AstraZeneca.
Well, in Clinical trials like these, Regulatory submissions are the most decisive milestone for a client like AstraZeneca in their clinical research. Quality regulatory document submissions can speed-up the time to market a drug, bring the advantage of new treatment to patients, and conserve patent life. At Turacoz Healthcare Solutions, Our team of medical writers have a clear understanding of the global regulatory requirements/expectations and International Conference on Harmonization (ICH) Good Clinical Practice (GCP) guidelines. Our medical writers are experienced in delivering protocols, investigational brochures, clinical study reports, and documents for IND and NDA submissions.
·         Study Synopsis and Protocol
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·         Informed consent form
·         Clinical study report (CSR)
·         Risk management plan (RMP)
·         Package Insert


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